Respiratory involvement in juvenile dermatomyositis

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Respiratory involvement in juvenile dermatomyositis

Materials and methods 16 patients (9 girls) with diagnosis of JDM (age 3–16,2 yrs) performed pulmonary function tests (PFT). 14 were receiving treatment; all had muscular testing. 13 had weakness as major symptom. Respiratory symptoms: dry cough in 2/16; reduced exercise tolerance: 3/16. Chest xray: normal in 13/13. Echocardiogram and ECG: normal in all. 9/16 had positive ANA-Ab; antiJO1 Ab neg...

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Dramatic heliotrope dermatitis and uncommon pulmonary involvement in juvenile dermatomyositis.

and interstitial lung disease is frequently identifi ed abnormality by CT. 3 Here we present a JDM case with severe heliotrope rash and uncommon manifestation in CT image of the lung. A 15-year-old girl presented with a 3-month history of progressive periorbital swelling and a reddishpurple rash on the upper and lower eyelids ( fi gure 1A ). Her vision acuity decreased and MRI showed only thick...

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Juvenile dermatomyositis.

Juvenile dermatomyositis (JDMS) is a chronic inflammatory condition characterized by muscle weakness and a distinctive rash caused by underlying vasculopathy. Long-term complications include subcutaneous and muscular calcification, contractures and in some cases the gradual development of a second connective tissue disease. Early aggressive treatment with systemic immunosuppressants and other a...

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Juvenile dermatomyositis.

The clinical profile of 7 children and their follow-up is described. There was female preponderance with mate to female ratio of 1:6. The median age of onset was 6 years. All the patients had skin rash, muscle weakness and abnormal enzyme profile. Muscle biopsy was performed in 6 and was abnormal in all of them. The electromyogram (EMG) was performed in 6 and was found abnormal in five. All the...

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Juvenile Dermatomyositis in Pregnancy

Juvenile dermatomyositis has variable clinical presentations both in and outside of pregnancy. A literature review indicated that optimal maternal and fetal outcomes can be anticipated when the pregnancy is undertaken while the disease is in remission. Poorer outcomes are associated with flare-up of the disease in early pregnancy compared with exacerbation in the second or third trimester, when...

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ژورنال

عنوان ژورنال: Pediatric Rheumatology

سال: 2008

ISSN: 1546-0096

DOI: 10.1186/1546-0096-6-s1-p219